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Well-being is received increased attention from people, researchers, and physicians. The main goal is to prevent the onset of pathologic health issues instead of using conventional pharmacological approaches unless absolutely necessary. Prevention and well-being are closely linked to the wrong lifestyle and dietary habits, which can determine the onset of illness. Some health conditions can be prevented and treated with the use of nutraceuticals in daily diet. Nutraceuticals are pharmacologically active substances that can be extracted from vegetable or animal products, and concentrated and administered in a suitable pharmaceutical form. A nutraceutical can provide beneficial health effects, e.g., the prevention and/or, in some cases, the treatment of disease. The key aspect is defining the range of possible uses for these new food-drugs and substantiation with in vitro and in vivo clinical data that support their efficacy, safety, and health benefits. This Special Issue is dedicated to assessing the sources, composition, formulation, use, experience in clinical use, mechanisms of action, and clinical data of nutraceuticals, which represent a new horizon for therapy and provide valuable tools to reduce the cost of the healthcare system, addressing resources for prevention rather than pharmacological therapy.

Research & information: general --- Biology, life sciences --- Food & society --- microalgae --- Spirulina --- Chlorella --- Klamath --- food supplement --- quality control --- cinnamon --- white adipocyte differentiation --- fatty acid oxidation --- lipogenesis --- adipogenesis --- red yeast rice --- lovastatin --- nutraceutical --- safety --- health --- HPLC --- wine --- polyphenols --- antioxidants --- hydroxytyrosol --- trans-resveratrol --- n/a --- EVOO --- biophenols --- oleuropein --- multivariate statistical analysis --- OPLS-DA --- food profiling --- β-polysaccharides --- antioxidant activity --- Opuntia ficus-indica --- cladodes --- pumpkin seed oil --- fatty acids --- stereospecific analysis --- sterols --- alcohols

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This Special Issue, entitled "Nutraceuticals and Functional Foods: Bridging Health and Food Under a New Perspective", aims to approach the current state-of-the-art research on nutraceuticals and functional foods. The main issue in this field of research is the sustainability and recovery of bioactive substances from vegetal- or animal-origin byproducts to project and realize novel food supplements and nutraceuticals. Low environmental impact, safety, new food sources and analytical methodologies are of growing interest in the research area of food.The perspective approach addresses the mechanism of action of nutraceuticals, safety and functional foods and nutraceuticals' mechanisms of action, revealing new possibilities for their use as tools in a complementary proactive approach to certain health issues to prevent the onset of health conditions or to be used in subjects who do not qualify for a conventional therapeutical approach. The areas involved in this perspective range from food chemistry and analysis to nutrition and from safety to sustainability; new therapeutical approaches and novel techniques of analysis and formulation are also involved, which require a wide inter- and multi-disciplinary approach. The overall assessment of these aspects creates new challenges for research and also impacts sustainability, health and safety. This Special Issue may also consider the bridging of health and food in their different declinations from a new perspective.

Chemistry, Technical

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Well-being is received increased attention from people, researchers, and physicians. The main goal is to prevent the onset of pathologic health issues instead of using conventional pharmacological approaches unless absolutely necessary. Prevention and well-being are closely linked to the wrong lifestyle and dietary habits, which can determine the onset of illness. Some health conditions can be prevented and treated with the use of nutraceuticals in daily diet. Nutraceuticals are pharmacologically active substances that can be extracted from vegetable or animal products, and concentrated and administered in a suitable pharmaceutical form. A nutraceutical can provide beneficial health effects, e.g., the prevention and/or, in some cases, the treatment of disease. The key aspect is defining the range of possible uses for these new food-drugs and substantiation with in vitro and in vivo clinical data that support their efficacy, safety, and health benefits. This Special Issue is dedicated to assessing the sources, composition, formulation, use, experience in clinical use, mechanisms of action, and clinical data of nutraceuticals, which represent a new horizon for therapy and provide valuable tools to reduce the cost of the healthcare system, addressing resources for prevention rather than pharmacological therapy.

microalgae --- Spirulina --- Chlorella --- Klamath --- food supplement --- quality control --- cinnamon --- white adipocyte differentiation --- fatty acid oxidation --- lipogenesis --- adipogenesis --- red yeast rice --- lovastatin --- nutraceutical --- safety --- health --- HPLC --- wine --- polyphenols --- antioxidants --- hydroxytyrosol --- trans-resveratrol --- n/a --- EVOO --- biophenols --- oleuropein --- multivariate statistical analysis --- OPLS-DA --- food profiling --- β-polysaccharides --- antioxidant activity --- Opuntia ficus-indica --- cladodes --- pumpkin seed oil --- fatty acids --- stereospecific analysis --- sterols --- alcohols